Specific action mediated by spinal HMGB1 receptors in the induction of central post-stroke pain
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چکیده
منابع مشابه
Is the pain modulatory action of 17β-estradiol in locus coeruleus of male rats is mediated by GABAA receptors?
Introduction: Estradiol is a neuroactive steroid, which is found in several brain areas such as locus coeruleus (LC). Estradiol modulates nociception by binding to its receptors and also by allosteric interaction with other membranebound receptors like glutamate and GABAA receptors. LC is involved in noradrenergic descending pain modulation. Methods: In order to study the effect of 17β-estra...
متن کاملThe Efficacy of Gabapentin in Patients with Central Post-stroke Pain
Thalamic pain syndrome, a type of central post-stroke pain (CPSP), may develops after a hemorrhagic or ischemic stroke and results in impairment of the thalamus. There is limited experience about gabapentin in treatment of central pains like CPSP.In a prospective observational study, the intensity of pain was recorded using the Numeric Rating Scale (NRS) at the entrance to the study. Patients e...
متن کاملEfficacy of Spinal Cord Stimulation for Central Post-Stroke Pain
Central post-stroke pain (CPSP) is a neuropathic-type of pain that affects about 1-8% of patients after stroke (Andersen et al., 1995; Bowsher 1993), and is characterized by pain and sensory dysfunction involving the area of the body that has been affected by the stroke (Leijon et al., 1998). Once present, CPSP rarely abates, causing a considerable long-term impact on patient’s quality of life ...
متن کاملThe Efficacy of Gabapentin in Patients with Central Post-stroke Pain
Thalamic pain syndrome, a type of central post-stroke pain (CPSP), may develops after a hemorrhagic or ischemic stroke and results in impairment of the thalamus. There is limited experience about gabapentin in treatment of central pains like CPSP.In a prospective observational study, the intensity of pain was recorded using the Numeric Rating Scale (NRS) at the entrance to the study. Patients e...
متن کاملThe Effects of Lamotrigine on Pain, Sleep, and Mood in Refractory Form of Central Post-Stroke Pain Syndrome
Background: Central post-stroke pain (CPSP) is a distressing pain syndrome, sometimes become refractory to the conventional pain managements. Anticonvulsants have been used to alleviate different central pains. Lamotrigine is a novel anticonvulsant and its proper dosage and its efficacy have not been well studied yet. The aim of this study was to evaluate the effect of 100 mg lamotrigine on ref...
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ژورنال
عنوان ژورنال: Proceedings for Annual Meeting of The Japanese Pharmacological Society
سال: 2018
ISSN: 2435-4953
DOI: 10.1254/jpssuppl.wcp2018.0_po3-2-7